Conventional versus ultrasound treat to target: no difference in magnetic resonance imaging inflammation or joint damage over 2 years in early rheumatoid arthritis

Conventional versus ultrasound treat to target: no difference in magnetic resonance imaging inflammation or joint damage over 2 years in early rheumatoid arthritis

Abstract Objective To investigate whether an ultrasound-guided treat-to-target strategy for early RA would lead to reduced MRI inflammation or less structural damage progression compared with a conventional treat-to-target strategy. Methods A total of 230 DMARD-naïve early RA patients were randomize...

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Veröffentlicht in:Rheumatology (Oxford, England) England), 2020-09, Vol.59 (9), p.2550-2555
Hauptverfasser: Sundin, Ulf, Aga, Anna-Birgitte, Skare, Øivind, Nordberg, Lena B, Uhlig, Till, Hammer, Hilde B, van der Heijde, Désirée, Kvien, Tore K, Lillegraven, Siri, Haavardsholm, Espen A
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Antirheumatic Agents - therapeutic use
Arthritis, Rheumatoid - diagnosis
Arthritis, Rheumatoid - drug therapy
Arthritis, Rheumatoid - physiopathology
Disease Progression
Female
Foot Joints - diagnostic imaging
Foot Joints - pathology
Functional Status
Hand Joints - diagnostic imaging
Hand Joints - pathology
Humans
Life Sciences & Biomedicine
Magnetic Resonance Imaging - methods
Male
Middle Aged
Outcome Assessment, Health Care
Radiography - methods
Remission Induction - methods
Rheumatology
Science & Technology
Synovitis - diagnosis
Synovitis - etiology
Tenosynovitis - diagnosis
Tenosynovitis - etiology
Ultrasonography, Doppler - methods
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Zusammenfassung:Abstract Objective To investigate whether an ultrasound-guided treat-to-target strategy for early RA would lead to reduced MRI inflammation or less structural damage progression compared with a conventional treat-to-target strategy. Methods A total of 230 DMARD-naïve early RA patients were randomized to an ultrasound tight control strategy targeting DAS
ISSN:1462-0324
1462-0332
DOI:10.1093/rheumatology/kez674