Effectiveness of myo-inositol oxygenase in the early diagnosis of experimental acute kidney injury

OBJECTIVES: The effectiveness of the myo-inositol oxygenase (MIOX) enzyme was investigated in the diagnosis of acute kidney injury (AKI). METHODS: In total, 40 rats were divided into 5 groups (n = 8, for each group) while left kidney ischemia-reperfusion was implemented in groups 2, 3, 4 and 5. Group 1 was the control group. Group 2 underwent 1-hour ischemia and 2-hour reperfusion. Group 3 underwent 1-hour ischemia and 4-hour reperfusion. Group 4 underwent 2-hour ischemia and 2-hour reperfusion. Group 5 underwent 2-hour ischemia and 4-hour reperfusion. RESULTS: Serum creatinine and blood urea nitrogen levels in all ischemia-reperfusion groups were higher than in the control group (p