Fabrication of Cylindrical Magnetic Nanoparticles for Functionalization of Polyelectrolyte Microcapsules

A problem of fabrication of magnetic polymer capsules for targeted drug delivery is considered. Magnetic nanoparticles are used in the problem under study. A method for fabrication of such particles involving synthesis of layered nanowires with alternating layers of the specified magnetic metal and...

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Veröffentlicht in:Technical physics 2020-09, Vol.65 (9), p.1377-1383
Hauptverfasser: Doludenko, I. M., Mikheev, A. V., Burmistrov, I. A., Trushina, D. B., Borodina, T. N., Bukreeva, T. V., Zagorskii, D. L.
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container_end_page 1383
container_issue 9
container_start_page 1377
container_title Technical physics
container_volume 65
creator Doludenko, I. M.
Mikheev, A. V.
Burmistrov, I. A.
Trushina, D. B.
Borodina, T. N.
Bukreeva, T. V.
Zagorskii, D. L.
description A problem of fabrication of magnetic polymer capsules for targeted drug delivery is considered. Magnetic nanoparticles are used in the problem under study. A method for fabrication of such particles involving synthesis of layered nanowires with alternating layers of the specified magnetic metal and sacrificial layers of nonmagnetic metal is proposed. A method for template-assisted synthesis based on ac-potential electroplating of specified metals in the pores of track membranes is used to fabricate wires with a diameter of 100 nm with nickel layers of 400 and 200 nm. A method for the subsequent extraction of nickel fragments using selective etching (removal) of copper fragments is developed. Procedures that prevent aggregation of magnetic nanoparticles and penetration of the nanoparticles in the shells of polymer capsules are considered.
doi_str_mv 10.1134/S1063784220090121
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subjects Classical and Continuum Physics
Drug delivery systems
Drugs
Electroplating
Ethylenediaminetetraacetic acid
Force and energy
Fragments
Nanomaterials in Biology and Medicine
Nanoparticles
Nanowires
Nickel
Physical Sciences
Physics
Physics and Astronomy
Physics, Applied
Polyelectrolytes
Polymers
Science & Technology
Synthesis
Vehicles
title Fabrication of Cylindrical Magnetic Nanoparticles for Functionalization of Polyelectrolyte Microcapsules
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