Fabrication of Cylindrical Magnetic Nanoparticles for Functionalization of Polyelectrolyte Microcapsules
A problem of fabrication of magnetic polymer capsules for targeted drug delivery is considered. Magnetic nanoparticles are used in the problem under study. A method for fabrication of such particles involving synthesis of layered nanowires with alternating layers of the specified magnetic metal and...
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Veröffentlicht in: | Technical physics 2020-09, Vol.65 (9), p.1377-1383 |
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creator | Doludenko, I. M. Mikheev, A. V. Burmistrov, I. A. Trushina, D. B. Borodina, T. N. Bukreeva, T. V. Zagorskii, D. L. |
description | A problem of fabrication of magnetic polymer capsules for targeted drug delivery is considered. Magnetic nanoparticles are used in the problem under study. A method for fabrication of such particles involving synthesis of layered nanowires with alternating layers of the specified magnetic metal and sacrificial layers of nonmagnetic metal is proposed. A method for template-assisted synthesis based on ac-potential electroplating of specified metals in the pores of track membranes is used to fabricate wires with a diameter of 100 nm with nickel layers of 400 and 200 nm. A method for the subsequent extraction of nickel fragments using selective etching (removal) of copper fragments is developed. Procedures that prevent aggregation of magnetic nanoparticles and penetration of the nanoparticles in the shells of polymer capsules are considered. |
doi_str_mv | 10.1134/S1063784220090121 |
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M. ; Mikheev, A. V. ; Burmistrov, I. A. ; Trushina, D. B. ; Borodina, T. N. ; Bukreeva, T. V. ; Zagorskii, D. L.</creator><creatorcontrib>Doludenko, I. M. ; Mikheev, A. V. ; Burmistrov, I. A. ; Trushina, D. B. ; Borodina, T. N. ; Bukreeva, T. V. ; Zagorskii, D. L.</creatorcontrib><description>A problem of fabrication of magnetic polymer capsules for targeted drug delivery is considered. Magnetic nanoparticles are used in the problem under study. A method for fabrication of such particles involving synthesis of layered nanowires with alternating layers of the specified magnetic metal and sacrificial layers of nonmagnetic metal is proposed. A method for template-assisted synthesis based on ac-potential electroplating of specified metals in the pores of track membranes is used to fabricate wires with a diameter of 100 nm with nickel layers of 400 and 200 nm. A method for the subsequent extraction of nickel fragments using selective etching (removal) of copper fragments is developed. 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A method for template-assisted synthesis based on ac-potential electroplating of specified metals in the pores of track membranes is used to fabricate wires with a diameter of 100 nm with nickel layers of 400 and 200 nm. A method for the subsequent extraction of nickel fragments using selective etching (removal) of copper fragments is developed. Procedures that prevent aggregation of magnetic nanoparticles and penetration of the nanoparticles in the shells of polymer capsules are considered.</description><subject>Classical and Continuum Physics</subject><subject>Drug delivery systems</subject><subject>Drugs</subject><subject>Electroplating</subject><subject>Ethylenediaminetetraacetic acid</subject><subject>Force and energy</subject><subject>Fragments</subject><subject>Nanomaterials in Biology and Medicine</subject><subject>Nanoparticles</subject><subject>Nanowires</subject><subject>Nickel</subject><subject>Physical Sciences</subject><subject>Physics</subject><subject>Physics and Astronomy</subject><subject>Physics, Applied</subject><subject>Polyelectrolytes</subject><subject>Polymers</subject><subject>Science & Technology</subject><subject>Synthesis</subject><subject>Vehicles</subject><issn>1063-7842</issn><issn>1090-6525</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>AOWDO</sourceid><recordid>eNqNkV9rFDEUxQdRsFY_gG8DPsrU3PzbmccyuCq0VrB9HjJ3b9aU2WRNMpT105txpUVUKHnI4eT8Ljf3VtVrYGcAQr77CkyLVSs5Z6xjwOFJdQJFNVpx9XTRWjTL-_PqRUq3jAG0Sp9U39ZmjA5NdsHXwdb9YXJ-szhTfWm2nrLD-rPxYW9ikROl2oZYr2ePC2Im9-Oe_RKmA02EORaRqb50GAOafZoL9rJ6Zs2U6NXv-7S6Wb-_7j82F1cfPvXnFw2KVuQGpNQ4EpeMWhKj7gxZ2xlkpX9QXSdGuwEsBhcj1xIlKgFGmRZXnRw3VpxWb4519zF8nynl4TbMsTSaBi4l1wCMy4fU1kw0OG9DjgZ3LuFwroVSjCkNJXX2j1Q5G9o5DJ6sK_4fAByB8vGUItlhH93OxMMAbFj2NPy1p8K0R-aOxmATOvJI9xxbCnesW8mimOxd_jXuPsw-F_Tt49GS5sd0Kgm_pfgwmf939xPHtrVo</recordid><startdate>20200901</startdate><enddate>20200901</enddate><creator>Doludenko, I. 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subjects | Classical and Continuum Physics Drug delivery systems Drugs Electroplating Ethylenediaminetetraacetic acid Force and energy Fragments Nanomaterials in Biology and Medicine Nanoparticles Nanowires Nickel Physical Sciences Physics Physics and Astronomy Physics, Applied Polyelectrolytes Polymers Science & Technology Synthesis Vehicles |
title | Fabrication of Cylindrical Magnetic Nanoparticles for Functionalization of Polyelectrolyte Microcapsules |
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