Fabrication of Cylindrical Magnetic Nanoparticles for Functionalization of Polyelectrolyte Microcapsules

A problem of fabrication of magnetic polymer capsules for targeted drug delivery is considered. Magnetic nanoparticles are used in the problem under study. A method for fabrication of such particles involving synthesis of layered nanowires with alternating layers of the specified magnetic metal and...

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Veröffentlicht in:Technical physics 2020-09, Vol.65 (9), p.1377-1383
Hauptverfasser: Doludenko, I. M., Mikheev, A. V., Burmistrov, I. A., Trushina, D. B., Borodina, T. N., Bukreeva, T. V., Zagorskii, D. L.
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Sprache:eng
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Zusammenfassung:A problem of fabrication of magnetic polymer capsules for targeted drug delivery is considered. Magnetic nanoparticles are used in the problem under study. A method for fabrication of such particles involving synthesis of layered nanowires with alternating layers of the specified magnetic metal and sacrificial layers of nonmagnetic metal is proposed. A method for template-assisted synthesis based on ac-potential electroplating of specified metals in the pores of track membranes is used to fabricate wires with a diameter of 100 nm with nickel layers of 400 and 200 nm. A method for the subsequent extraction of nickel fragments using selective etching (removal) of copper fragments is developed. Procedures that prevent aggregation of magnetic nanoparticles and penetration of the nanoparticles in the shells of polymer capsules are considered.
ISSN:1063-7842
1090-6525
DOI:10.1134/S1063784220090121