Abnormal body composition is a predictor of adverse outcomes after autologous haematopoietic cell transplantation

Background The number of patients undergoing autologous haematopoietic cell transplant (HCT) is growing, but little is known about the factors that predict adverse outcomes. Low muscle mass and obesity are associated with disability and premature mortality in individuals with non‐malignant diseases...

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Veröffentlicht in:	Journal of cachexia, sarcopenia and muscle sarcopenia and muscle, 2020-08, Vol.11 (4), p.962-972
Hauptverfasser:	Armenian, Saro H., Iukuridze, Aleksi, Teh, Jennifer Berano, Mascarenhas, Kristen, Herrera, Alex, McCune, Jeannine S., Zain, Jasmine M., Mostoufi‐Moab, Sogol, McCormack, Shana, Slavin, Thomas P., Scott, Jessica M., Jones, Lee W., Sun, Can‐Lan, Forman, Stephen J., Wong, F. Lennie, Nakamura, Ryotaro
Format:	Artikel
Sprache:	eng
Schlagworte:	Abdomen Adolescent Adult Aged Body composition Body Composition - physiology Body mass index Cohort Studies Comorbidity complications Demographics Ethnicity Female General & Internal Medicine Geriatrics & Gerontology Haematopoietic cell transplantation Hematopoietic Stem Cell Transplantation - adverse effects Hematopoietic Stem Cell Transplantation - methods Hospitalization Hospitals Humans Life Sciences & Biomedicine Lymphoma Male Medical records Medicine, General & Internal Middle Aged Mortality Musculoskeletal system Obesity Original Patients Researchers Retrospective Studies Sarcopenia Science & Technology Software Studies Transplantation Conditioning - adverse effects Transplantation Conditioning - methods Transplantation, Autologous - adverse effects Transplantation, Autologous - methods Transplants & implants Vertebrae Young Adult
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Zusammenfassung:	Background The number of patients undergoing autologous haematopoietic cell transplant (HCT) is growing, but little is known about the factors that predict adverse outcomes. Low muscle mass and obesity are associated with disability and premature mortality in individuals with non‐malignant diseases and may predict outcomes after autologous HCT. Methods This was a retrospective cohort study of 320 patients who underwent autologous HCT for Hodgkin or non‐Hodgkin lymphoma between 2009 and 2014. Sarcopenia {skeletal muscle index male:
ISSN:	2190-5991 2190-6009
DOI:	10.1002/jcsm.12570