Sufentanil and remifentanil combined with dezocine anesthesia for radical resection of liver cancer and its effect on liver and kidney function

Objective: To study the effect of sufentanil and remifentanil combined with dezocine on radical resection of liver cancer and its effect on liver and kidney function. Methods: Altogether 137 patients who underwent radical resection of liver cancer in Hanchuan Traditional Chinese Medicine Hospital of Hubei from February 2016 to June 2018 were collected; 72 of whom were treated with sufentanil combined with dezocine as the observation group (OG) and 65 of whom were treated with remifentanil combined with dezocine as the control group (CG). The stress state, VAS score, liver and kidney function index and postoperative adverse reactions of the two groups were observed 15 minutes before anesthesia (T0), at skin incision (T1), at surgery completion (T2) and 24 hours (T3) after operation. Results: The stress state of the OG at T1, T2 and T3 was greatly lower than that of the CG, and the VAS score of the OG was lower than that of the CG. There was no remarkable difference in adverse reactions between the two groups, and no difference in liver function indicators ALT, AST and renal function indicators Cr and BUN. Conclusion: Sufentanil combined with dezocine can provide more stable hemodynamics, reduce stress responses and reduce postoperative pain, but there is no difference in the liver and kidney function compared with remifentanil.