Regulation of immune-driven pathogenesis in Parkinson’s disease by gut microbiota

•T-cell-driven immunity and inflammation plays a role in PD pathogenesis.•α-syn acts as triggers of T-cell mediated immunity.•Gut microbiota triggers α-syn aggregation.•Gut microbiota regulates T-cell mediated immunity and inflammation.•Gut microbiota regulates the integrity of blood brain barrier....

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Veröffentlicht in:	Brain, behavior, and immunity behavior, and immunity, 2020-07, Vol.87, p.890-897
Hauptverfasser:	Zheng, Wenxia, He, Rongni, Yan, Zhenxing, Huang, Yaowei, Huang, Wei, Cai, Zhuoyi, Su, Yuying, Liu, Siqin, Deng, Yiting, Wang, Qing, Xie, Huifang
Format:	Artikel
Sprache:	eng
Schlagworte:	Gastrointestinal Microbiome Gut microbiota Humans Immunity Immunology Life Sciences & Biomedicine Neurosciences Neurosciences & Neurology Parkinson Disease Parkinson’s disease Psychiatry Science & Technology T cells
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