Effect of Bushen Guchi Pills on alveolar bone reconstruction in rats with periodontitis

Objective: This study was designed to analyze the effects of Bushen Guchi Pills on remodeling the alveolar bone of rats with paradentitis. Methods: Thirty healthy adult SD rats were included and randomized into three groups. Two groups were processed as models of rats with paradentitis, and further divided into the model group, subject to no treatment and the treatment group, with Bushen Guchi Pills. The 3rd group was the control group consisting of normal rats without any treatment. The three groups were compared for alveolar bone remodeling, serum bone turnover markers and Micro-CT examination results. Results: One month after treatment, an ascending order was established as the treatment group, the model group and the normal group for osteocalcin (OCN) (P