Altered Interactions Among Resting‐State Networks in Individuals with Obesity

Objective The aim of this study was to investigate alterations in functional connectivity (FC) within and interactions between resting‐state networks involved in salience, executive control, and interoception in participants with obesity (OB). Methods Using resting‐state functional magnetic resonance imaging with independent component analysis and FC, alterations within and interactions between resting‐state networks in 35 OB and 35 normal‐weight controls (NW) were investigated. Results Compared with NW, OB showed reduced FC strength in the ventromedial prefrontal cortex and posterior cingulate cortex/precuneus within the default‐mode network, dorsal anterior cingulate cortex within the salience network (SN), bilateral dorsolateral prefrontal cortex‐angular gyrus within the frontoparietal network (FPN), and increased FC strength in the insula (INS) (Pfamilywise error