MnOx MFs as a coreaction accelerator for the construction of a novel ternary electrochemiluminescence system: ultrasensitive detection of microRNA

MnOx MFs as a coreaction accelerator for the construction of a novel ternary electrochemiluminescence system: ultrasensitive detection of microRNA

By using multivalent manganese oxides microflowers (MnOx MFs) as prominent a coreaction accelerator in luminol/dissolved oxygen system, and by combining these with DNA nanostructures for efficient immobilization of the electrochemiluminescence (ECL) quencher doxorubicin-ferrocenecarboxylic acid (Dox...

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Veröffentlicht in:Chemical communications (Cambridge, England) England), 2020, Vol.56 (6), p.976-979
Hauptverfasser: Yang, Rong, Liu, Jia-Li, Chai, Ya-Qin, Yuan, Ruo
Format: Artikel
Sprache:eng
Schlagworte:
Chemistry
Chemistry, Multidisciplinary
Doxorubicin
Electrochemiluminescence
Manganese
MicroRNAs
Physical Sciences
Ribonucleic acid
RNA
Science & Technology
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Zusammenfassung:By using multivalent manganese oxides microflowers (MnOx MFs) as prominent a coreaction accelerator in luminol/dissolved oxygen system, and by combining these with DNA nanostructures for efficient immobilization of the electrochemiluminescence (ECL) quencher doxorubicin-ferrocenecarboxylic acid (Dox-FcCOOH), an ultrasensitive biosensing platform was constructed to conduct a microRNA assay in tumour cells.
ISSN:1359-7345
1364-548X
DOI:10.1039/c9cc08433a