Genetic characterization of 19 X-STRs in Sierra Leone population from Freetown

A total of 550 individuals (265 males and 285 females) from Sierra Leone, a west-African coastal country, were genotyped using the Microreader™ 19X ID System kit. No significant deviations from the Hardy-Weinberg equilibrium were observed. A total of 250 alleles were identified with corresponding al...

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Veröffentlicht in:International journal of legal medicine 2020-09, Vol.134 (5), p.1659-1661
Hauptverfasser: Lin, Lin, Li, Jienan, Hu, Yize, Wang, Han, Marah, Foday Ambrose, Moseray, Moses, Kureshi, Aliye, Wang, Chudong, Zeye, Moutanou Modeste Judes, Zha, Lagabaiyila
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Sprache:eng
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Zusammenfassung:A total of 550 individuals (265 males and 285 females) from Sierra Leone, a west-African coastal country, were genotyped using the Microreader™ 19X ID System kit. No significant deviations from the Hardy-Weinberg equilibrium were observed. A total of 250 alleles were identified with corresponding allele frequencies spanning from 0.0012 to 0.6762. PIC of the loci ranged from 0.4615 to 0.9481. The CPE, CPD F , and CPD M were 0.9999997856, 0.999999999999999999995774, and 0.999999999998997, respectively. The highly combined MEC Kruger , MEC Kishida , MEC Desmarais , and MEC Desmarais Duo were achieved as 0.99999992508, 0.999999999990802, 0.999999999990836, and 0.99999998412, respectively. Genetic comparisons revealed that genetic homogeneity existed in similar ethno origin or geographic origin populations. This is a pioneering genetic investigation using the Microreader™ 19X ID System kit in the population of Sierra Leone.
ISSN:0937-9827
1437-1596
DOI:10.1007/s00414-019-02243-6