Genetic characterization of 19 X-STRs in Sierra Leone population from Freetown
A total of 550 individuals (265 males and 285 females) from Sierra Leone, a west-African coastal country, were genotyped using the Microreader™ 19X ID System kit. No significant deviations from the Hardy-Weinberg equilibrium were observed. A total of 250 alleles were identified with corresponding al...
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Veröffentlicht in: | International journal of legal medicine 2020-09, Vol.134 (5), p.1659-1661 |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | A total of 550 individuals (265 males and 285 females) from Sierra Leone, a west-African coastal country, were genotyped using the Microreader™ 19X ID System kit. No significant deviations from the Hardy-Weinberg equilibrium were observed. A total of 250 alleles were identified with corresponding allele frequencies spanning from 0.0012 to 0.6762. PIC of the loci ranged from 0.4615 to 0.9481. The CPE, CPD
F
, and CPD
M
were 0.9999997856, 0.999999999999999999995774, and 0.999999999998997, respectively. The highly combined MEC
Kruger
, MEC
Kishida
, MEC
Desmarais
, and MEC
Desmarais Duo
were achieved as 0.99999992508, 0.999999999990802, 0.999999999990836, and 0.99999998412, respectively. Genetic comparisons revealed that genetic homogeneity existed in similar ethno origin or geographic origin populations. This is a pioneering genetic investigation using the Microreader™ 19X ID System kit in the population of Sierra Leone. |
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ISSN: | 0937-9827 1437-1596 |
DOI: | 10.1007/s00414-019-02243-6 |