The clinical spectrum of dermatomyositis and the new autoantibodies – with regard to two clinical cases with distinct associations

Dermatomyositis is a rare idiopathic inflammatory myopathy associated with different autoantibodies (anti‐MDA5, anti‐TIF1‐γ) which are linked with typical and distinct phenotypes of dermatomyositis. We describe two cases that illustrate these diverse cutaneous and systemic manifestations.

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Bibliographische Detailangaben
Veröffentlicht in:	Australasian journal of dermatology 2020-05, Vol.61 (2), p.e241-e243
Hauptverfasser:	Calvão da Silva, Joana Cruz Matos, Santiago, Luís, Brites, Maria Manuel, Gonçalo, Margarida
Format:	Artikel
Sprache:	eng
Schlagworte:	Autoantibodies Autoantibodies - immunology Dermatology Dermatomyositis Dermatomyositis - immunology Disease Progression Female Humans Inflammation Interferon-Induced Helicase, IFIH1 - immunology Life Sciences & Biomedicine Male MDA5 Middle Aged Myopathy Nuclear Proteins - immunology paraneoplastic Phenotypes Science & Technology TIF1 Transcription Factors - immunology
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Beschreibung
Zusammenfassung:	Dermatomyositis is a rare idiopathic inflammatory myopathy associated with different autoantibodies (anti‐MDA5, anti‐TIF1‐γ) which are linked with typical and distinct phenotypes of dermatomyositis. We describe two cases that illustrate these diverse cutaneous and systemic manifestations.
ISSN:	0004-8380 1440-0960
DOI:	10.1111/ajd.13232