Projection capacity assessment of hyaluronic acid fillers

Aim: Hyaluronic acid (HA) is considered as the gold standard biomaterial for facial soft tissue correction. Over the last 8 years, there has been a strong demand from physicians for HA products with high projection capacity to restore facial volume loss at the level of the cheeks, cheekbones, chin, temples and jawlines. The projection capacity is thus an essential property for HA fillers especially for the products dedicated to the restoration of the volume of the face. Methods: ln this publication, a new skin model assay for evaluating the projection capacity of HA fillers is presented, applied and discussed. Results: This skin model assay enables to efficiently assess the projection capacity of a HA filler product. The comparative evaluation of a product benefiting from the novel OXlFREE technology and Juvéderm Voluma shows a higher projection capacity for the OXlFREE product than for Juvéderm Voluma. Conclusion: This assay is demonstrated to be a key tool to guide physicians in the selection of products with high ability of tissue projection to optimize their aesthetic outcomes when they need to create facial volume.