Chemical Constituents of the Roots of Vernonia cumingiana Benth

: To search for new and bioactive constituents from traditional Chinese medicines, a new steroidal saponin, named vernonioside G (1), was isolated from the roots of Vernonia cumingiana Benth. (Compositae). The structure of vernonioside G was elucidated using spectral methods, particularly two‐dimensional nuclear magnetic resonance analysis. Together with the new compound, eight known compounds were also isolated and identified from the roots of V. cumingiana, among which, VE‐1 (2) and 24‐methylenelanost‐9(11)‐en‐3β‐ol acetate (3) were assigned NMR data for the first time and compound 3 was obtained as a natural product from a plant for the first time. (Managing editor: Wei WANG)