Micro-computed tomography for small animal imaging: Technological details

The high-resolution micro-computed tomography (micro-CT) system has now become an important tool for biological research. The micro-CT system enables a non-invasive inspection to screen anatomical changes in small animals. The promising advantages include high-spatial resolution, high sensitivity to...

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Veröffentlicht in:Progress in natural science 2008, Vol.18 (5), p.513-521
Hauptverfasser: Li, Hao, Zhang, Hui, Tang, Zhiwei, Hu, Guangshu
Format: Artikel
Sprache:eng
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Zusammenfassung:The high-resolution micro-computed tomography (micro-CT) system has now become an important tool for biological research. The micro-CT system enables a non-invasive inspection to screen anatomical changes in small animals. The promising advantages include high-spatial resolution, high sensitivity to bone and lung, short scan time and cost-effectiveness. The dose received by the small animal might be a critical concern in the research. In this article, the choice of the components, fundamental physical problems, the image reconstruction algorithm and the representative applications of micro-CT are summarized. Some results from our research group are also presented to show high-resolution images obtained bv the micro-CT svstem.
ISSN:1002-0071
DOI:10.1016/j.pnsc.2008.01.002