185例真性红细胞增多症的临床分析

目的:了解真性红细胞增多症(PV)患者临床特点及疾病自然过程。方法:分析185例PV患者临床症状、体征、实验室检查及转归。结果:185例患者中,男122例,女63例。发病年龄(52.7±14.1)岁。初诊时血红蛋白为(208.3±21.2)g/L。血常规三系增高74例(40.0%),单纯血红蛋白增高33例(17.8%),血红蛋白增高伴有白细胞增高67例(36.2%),血红蛋白增高伴有血小板增高11例(5.9%)。脾大(66.5%),肝大3例916.2)。25例患者检测Epo水平,9例(36.0)正常,16例(64.0%)减低。30例患者进行干/祖细胞培养,57% CFU-E增高,59% BFU...

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Veröffentlicht in:Zhōnghuá xuèyèxué zázhì 2002, Vol.23 (11), p.578-580
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description 目的:了解真性红细胞增多症(PV)患者临床特点及疾病自然过程。方法:分析185例PV患者临床症状、体征、实验室检查及转归。结果:185例患者中,男122例,女63例。发病年龄(52.7±14.1)岁。初诊时血红蛋白为(208.3±21.2)g/L。血常规三系增高74例(40.0%),单纯血红蛋白增高33例(17.8%),血红蛋白增高伴有白细胞增高67例(36.2%),血红蛋白增高伴有血小板增高11例(5.9%)。脾大(66.5%),肝大3例916.2)。25例患者检测Epo水平,9例(36.0)正常,16例(64.0%)减低。30例患者进行干/祖细胞培养,57% CFU-E增高,59% BFU-E增高,其中11例检测内源性红系集落(EEC),10例(90.9%)出现EEC。82例(44.3%)发生血栓栓塞103次,5例进展为骨髓纤维化(MF),1例发生继发肿瘤,2例死于栓塞。结论:PV是一种成年型骨髓增殖性疾病,极易并发栓塞,易检出EEC,且血清Epo水平多减低,主要进展为MF。
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subjects 临床分析
治疗
症状
真性红细胞增多症
诊断
title 185例真性红细胞增多症的临床分析
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