Laser confocal microscopy findings of Thygeson superficial punctate keratitis

Thygeson superficial punctate keratitis （TSPK） is a rare,chronic,inflammatory disorder,with adverse impact on the visual function and quality of life in patients.It was first described by Thygeson in 1950,1 as typically bilateral,corneal epithelial opacities without associated stromal involvement or corneal edema.Recurrent episodes of tearing,foreign body sensation,photophobia,and reduced vision are observed.To date,virus infection and immune factors have been considered as important risk factors for visual deterioration in the patients with TSPK,but the origin of the comeal opacities remains poorly understood.Keywords：Thygeson superficial punctate keratitis ; laser confocal microscopy