CRABP2 and FABP5 identified by 2D DIGE profiling are upregulated in human bladder cancer

Bladder cancer （BC） is the second most common malignancy of the human genitourinary tract,and is characterized by a high recurrence rate and expensive treatment） There is still no ideal biomarker for diagnosing or monitoring human BC.In the present study,we used proteomics analysis,including two-dimensional fluorescence difference gel electrophoresis （2D DIGE） and matrix-assisted laser desorption ionization time of flight/time of flight mass spectrometry （MALDI-TOF/TOF MS）,to identify new potential protein markers of BC.