Back to the future： drug eluting balloon in bifurcation intervention

Atherosclerotic process has a predilection for .bifurcation due to the complex hemodynamics and resultant altered shear stress that contributes to the localization and progression of atheromatous plaques. Coronary intervention, especially the placement of stents further alters the hemodynamics and shear forces. These factors may account for the increased incidences of in-stent restenosis, stent thrombosis, side-branch （SB） restenosis, etc, that continue to plague bifurcation intervention.