Using intra-operative GeneSearchTM Breast Lymph Node Assay to detect breast cancer metastases in sentinel lymph nodes： results from a single institute in China

Background Sentinel lymph node （SLN） biopsy has become a common procedure for early breast cancer patients. The GeneSearchTM Breast Lymph Node （BLN） Assay is a real-time RT-PCR assay for the detecting nodal metastases larger than 0.2 mm. China Breast Cancer Clinical Study Group （CBCSG）-001a is a pro...

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Veröffentlicht in:	Chinese medical journal 2011-04, Vol.124 (7), p.973-977
Hauptverfasser:	Sun, Xiao, Liu, Juan-Juan, Wang, Yong-Sheng, Song, Xian-Rang, Zhong, Wei-Xia, Zhou, Chang-Chun, Mu, Dian-Bin, Zuo, Wen-Shu, Yu, Zhi-Yong, Zhou, Zheng-Bo
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Breast Neoplasms - complications Female Humans Lymph Nodes - pathology Lymphatic Metastasis - diagnosis Middle Aged PCR检测 Sentinel Lymph Node Biopsy - methods 中国临床试验乳腺癌手术淋巴结研究所试验检测
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Beschreibung
Zusammenfassung:	Background Sentinel lymph node （SLN） biopsy has become a common procedure for early breast cancer patients. The GeneSearchTM Breast Lymph Node （BLN） Assay is a real-time RT-PCR assay for the detecting nodal metastases larger than 0.2 mm. China Breast Cancer Clinical Study Group （CBCSG）-001a is a prospective multi-center clinical trial that was conducted to validate the GeneSearchTM BLN Assay in China.
ISSN:	0366-6999 2542-5641
DOI:	10.3760/cma.j.issn.0366-6999.2011.07.004