HIV-1 DNA vaccine with adjuvant cytokines induces specific immune responses against HIV-1 infection in mice

There is mounting evidence that the induction of strong mucosal and cell-mediated immune responses is key element to consider in constructing efficacious HIV-1 vaccine. Therapeutic vaccines that induce high levels of CTL specific to HIV are currently being developed worldwide.

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Bibliographische Detailangaben
Veröffentlicht in:	Chinese medical journal 2006-06, Vol.119 (12), p.1034-1037
Hauptverfasser:	Wang, Fu-xiang, Sun, Yong-tao, Wang, Lin-xu, Liu, Juan
Format:	Artikel
Sprache:	eng
Schlagworte:	AIDS Vaccines - immunology Animals Cytokines - genetics Female HIV-1 - immunology Immunization Interferon-gamma - blood Lymphocyte Activation Mice Mice, Inbred BALB C Plasmids Vaccines, DNA - immunology 免疫反应爱滋病细胞因子细胞活素类
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Beschreibung
Zusammenfassung:	There is mounting evidence that the induction of strong mucosal and cell-mediated immune responses is key element to consider in constructing efficacious HIV-1 vaccine. Therapeutic vaccines that induce high levels of CTL specific to HIV are currently being developed worldwide.
ISSN:	0366-6999 2542-5641
DOI:	10.1097/00029330-200606020-00012