Multiple sclerosis after hepatitis B vaccination in a 16- year-old patient

Since the first description of multiple sclerosis （MS）, it has been known that relapse of the disease may be triggered by febrile infections. Although the prevention of febrile illness is therefore clearly advantageous for those with MS there is considerable controversy as to whether vaccine should be administered to such individuals. A further subject of debate is the possibility that vaccination （against influenza,