Immune response in Balb／c mice induced by recombinant spike protein of severe acute respiratory syndrome coronavirus

Severe acute respiratory syndrome coronavirus (SARS-CoV) is a highly aggressive pathogen that caused SARS in 2003 and 2004. Spike protein (S) on the surface of virus particles mediates the attachment of the virus to cell surface receptors and induces the fusion of viral and cellular membranes.

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Bibliographische Detailangaben
Veröffentlicht in:	Chinese medical journal 2005-05, Vol.118 (10), p.857-860
Hauptverfasser:	Qin, Li, Wu, Shao-ting, Wang, Xi-ming, Yuan, Shi-shan, Huang, Da-na, Lei, Ming-jun, Pan, Hui-rong, Lin, Qi-ping, Gao, Shi-tong, Zhang, Ren-li, Qu, Shen
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Viral - blood Balb／c Cytokines - blood Female Immunoglobulin G - blood Immunoglobulin G - classification Membrane Glycoproteins - immunology Mice Mice, Inbred BALB C Recombinant Proteins - immunology Severe Acute Respiratory Syndrome - immunology Spike Glycoprotein, Coronavirus T-Lymphocyte Subsets - immunology Viral Envelope Proteins - immunology 严重急性呼吸综合征免疫反应冠状病毒动物实验重组蛋白
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Beschreibung
Zusammenfassung:	Severe acute respiratory syndrome coronavirus (SARS-CoV) is a highly aggressive pathogen that caused SARS in 2003 and 2004. Spike protein (S) on the surface of virus particles mediates the attachment of the virus to cell surface receptors and induces the fusion of viral and cellular membranes.
ISSN:	0366-6999 2542-5641