Analysis and Interpretation of Detection Results of Novel Coronavirus Nucleic Acids and Specific Antibodies

The novel coronavirus (2019 novel coronavirus, 2019-nCoV) is a newly emerged virus. Therefore, the nucleic acid detection technology and serum immunological detection technology established urgently in emergencies have certain defects inevitably. The efficiency of nucleic acid and antibody detection...

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Veröffentlicht in:中国生物医学工程学报(英文版) 2020, Vol.29 (1), p.34-38
Hauptverfasser: Dongliang Li, Jia Ye, Yunhua Yu, Guoqing Yu, Chuanshen Jiang, Xianliang Lin, Wenfeng Lin, Youguang Lu
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Sprache:eng
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Zusammenfassung:The novel coronavirus (2019 novel coronavirus, 2019-nCoV) is a newly emerged virus. Therefore, the nucleic acid detection technology and serum immunological detection technology established urgently in emergencies have certain defects inevitably. The efficiency of nucleic acid and antibody detection varies at different stages of disease progression of the novel coronavirus disease (COVID-19). If the two can be used in combination and the results of the analysis can be comprehen-sively judged, they can be combined to monitor the viral load and disease progress better and improve the diagnostic effi-ciency. Based on the author's application experience, this article analyzes and interprets eight common modes of combined detection of nucleic acids and specific antibodies in order to provide a reference for the clinical diagnosis and treatment of COVID-19.
ISSN:1004-0552