Membrane-targeting amphiphilic AIE photosensitizer for broad-spectrum bacteria imaging and photodynamic killing of bacteria

An amphiphilic AIE photosensitizer has been successfully developed, which allows for easily inserting into the bacterial membranes. Binding experiments with phospholipid preliminary demonstrates its membrane specificity. As expected, it is proved to possess a broad-spectrum bacterial staining perfor...

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Veröffentlicht in:Chinese chemical letters 2023-09, Vol.34 (9), p.108160-201, Article 108160
Hauptverfasser: Zhang, Haining, He, Chaojun, Shen, Limin, Tao, Wenjun, Zhu, Jianhui, Song, Jinzhao, Li, Ziyong, Yin, Jun
Format: Artikel
Sprache:eng
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Zusammenfassung:An amphiphilic AIE photosensitizer has been successfully developed, which allows for easily inserting into the bacterial membranes. Binding experiments with phospholipid preliminary demonstrates its membrane specificity. As expected, it is proved to possess a broad-spectrum bacterial staining performance and photodynamic antibacterial activity toward S. aureus and E. coli. [Display omitted]
ISSN:1001-8417
1878-5964
DOI:10.1016/j.cclet.2023.108160