Electrochemical synthesis of 3-azido-indolines from amino-azidation of alkenes

An electrochemical amino-azidolation of 2-aminostyrene with sodium azide (NaN3) was developed. The reaction can be carried out smoothly in water under metal-free condition. A series 3-azido indolines can be obtained with high yields. [Display omitted] An electrochemical amino-azidation of 2-aminosty...

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Veröffentlicht in:Chinese chemical letters 2021-03, Vol.32 (3), p.1033-1036
Hauptverfasser: Guo, Shengping, Liu, Liyan, Hu, Kangfei, Sun, Qi, Zha, Zhenggen, Yang, Yu, Wang, Zhiyong
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Sprache:eng
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Zusammenfassung:An electrochemical amino-azidolation of 2-aminostyrene with sodium azide (NaN3) was developed. The reaction can be carried out smoothly in water under metal-free condition. A series 3-azido indolines can be obtained with high yields. [Display omitted] An electrochemical amino-azidation of 2-aminostyrene with sodium azide (NaN3) was developed, which can be carried out smoothly in water under metal-free condition, affording a series of 3-azido indolines with high yields.
ISSN:1001-8417
1878-5964
DOI:10.1016/j.cclet.2020.09.041