Synthesis of polysubstituted pyrroles via a gold(I)-catalyzed tandem three-component reaction at room temperature
A gold(I)-catalyzed three-component reaction of β-nitrostyrenes with 1,3-dicarbonyl compounds and primary amines to form polysubstituted pyrroles has been developed at room temperature in ethanol. The key advantages of the three-component reaction are the mild reaction conditions and environmentally...
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Veröffentlicht in: | Chinese chemical letters 2018-12, Vol.29 (12), p.1893-1896 |
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Hauptverfasser: | , , , , , , , |
Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | A gold(I)-catalyzed three-component reaction of β-nitrostyrenes with 1,3-dicarbonyl compounds and primary amines to form polysubstituted pyrroles has been developed at room temperature in ethanol. The key advantages of the three-component reaction are the mild reaction conditions and environmentally safer solvent
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A gold(I)-catalyzed three-component reaction of β-nitrostyrenes with 1,3-dicarbonyl compounds and primary amines to form polysubstituted pyrroles has been developed at room temperature in ethanol. The key advantages of the three-component reaction are the mild reaction conditions and environmentally safer solvent. |
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ISSN: | 1001-8417 1878-5964 |
DOI: | 10.1016/j.cclet.2018.09.004 |