Synthesis of a dendritic estrogen cluster： A potential tool for studies of nuclear versus extranuclear pathways of estrogen actions

Synthesis of a dendritic estrogen cluster： A potential tool for studies of nuclear versus extranuclear pathways of estrogen actions

A novel estrogen dendrimer has been synthesized through a combination of divergent and convergent approaches in 9 practical steps and in good yields. It was characterized and confirmed by elemental analysis, FT-IR, MS, 1H NMR, 13C NMR. The dendrimer contains 16 estrone units and is potentially a use...

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Veröffentlicht in:Chinese chemical letters 2012-12, Vol.23 (12), p.1319-1322
Hauptverfasser: Chen, Jian, Zheng, Hu, Song, Yan, Liang, Yu Feng, Qi, Qing Rong
Format: Artikel
Sprache:eng
Schlagworte:
Estrogen dendrimer
FT-IR
Nuclear and extranuclear
Receptor
Synthesis
合成
工具
树枝状大分子
树突
核外电子
集群
雌激素
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Zusammenfassung:A novel estrogen dendrimer has been synthesized through a combination of divergent and convergent approaches in 9 practical steps and in good yields. It was characterized and confirmed by elemental analysis, FT-IR, MS, 1H NMR, 13C NMR. The dendrimer contains 16 estrone units and is potentially a useful tool for the studies of estrogen actions.
ISSN:1001-8417
1878-5964
DOI:10.1016/j.cclet.2012.11.009