Copper-catalyzed synthesis of 1,2-disubstituted benzimidazoles from imidoyl chlorides

Copper-catalyzed synthesis of 1,2-disubstituted benzimidazoles from imidoyl chlorides

A strategy for the synthesis of 1,2-disubstituted benzimidazoles has been developed and a variety of 1,2-disubstituted benzimidazoles were obtained from imidoyl chlorides and o-haloanilines via copper（I）-catalyzed reaction in moderate yields.

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Veröffentlicht in:Chinese chemical letters 2012-05, Vol.23 (5), p.573-575
Hauptverfasser: Yu, Hui, Zhang, Mei Shu, Cui, Li Ren
Format: Artikel
Sprache:eng
Schlagworte:
1,2-Disubstituted benzimidazole
Copper(I)-catalysis
Imidoyl chloride
催化反应
催化合成
取代苯并咪唑
氯化物
铜（I）
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Zusammenfassung:A strategy for the synthesis of 1,2-disubstituted benzimidazoles has been developed and a variety of 1,2-disubstituted benzimidazoles were obtained from imidoyl chlorides and o-haloanilines via copper（I）-catalyzed reaction in moderate yields.
ISSN:1001-8417
1878-5964
DOI:10.1016/j.cclet.2012.02.008