An efficient and solvent-free one-pot synthesis of 1,4-dihydropyridines under microwave irradiation
An efficient synthesis of 1,4-dihydropyridines using lanthanum oxide as a catalyst from aldehydes,β-ketoester and ammonium acetate without solvent under the irradiation of microwave is described.Compared with the classical Hantzsch reaction,this new method has the advantage of good yield（90-98%） and...
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| Veröffentlicht in: | Chinese chemical letters 2011-10, Vol.22 (10), p.1199-1202 |
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| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
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| Online-Zugang: | Volltext |
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| Zusammenfassung: | An efficient synthesis of 1,4-dihydropyridines using lanthanum oxide as a catalyst from aldehydes,β-ketoester and ammonium acetate without solvent under the irradiation of microwave is described.Compared with the classical Hantzsch reaction,this new method has the advantage of good yield（90-98%） and short reaction time（40-80 s）. |
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| ISSN: | 1001-8417 1878-5964 |
| DOI: | 10.1016/j.cclet.2011.05.003 |