The convenient synthesis of 4-arylmethylidene-4,5- dihydro-3-phenylisoxazol-5-ones
4-Arylmethylidene-4,5-dihydro-3-phenylisoxazol-5-ones were synthesized by the convenient three-component reaction of ethyl benzoylacetate, hydroxylamine and aromatic aldehydes in the presence of pyridine. The target compounds were also obtained by the reaction between 3-phenylisoxazol-5-one and arom...
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Veröffentlicht in: | Chinese chemical letters 2011-02, Vol.22 (2), p.151-154 |
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Hauptverfasser: | , |
Format: | Artikel |
Sprache: | eng |
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Online-Zugang: | Volltext |
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Zusammenfassung: | 4-Arylmethylidene-4,5-dihydro-3-phenylisoxazol-5-ones were synthesized by the convenient three-component reaction of ethyl benzoylacetate, hydroxylamine and aromatic aldehydes in the presence of pyridine. The target compounds were also obtained by the reaction between 3-phenylisoxazol-5-one and aromatic aldehydes at 105
°C under solvent free condition. Yields of products depended considerably on the aldehyde used. |
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ISSN: | 1001-8417 1878-5964 |
DOI: | 10.1016/j.cclet.2010.09.023 |