High performance liquid chromatographic separation of clausenamide enantiomers with chiral-AGP stationary phase

A method of high performance liquid chromatographic separation of clausenamide enantiomers with chiral-AGP（α_1-acid glycoprotein） stationary phases has been established.The absolute configurations of（-）clausenamide and（＋）clausenamide are 3S, 4R,5R,6S and 3R,4S,5S,6R,respectively.The present method h...

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Veröffentlicht in:	Chinese chemical letters 2010-07, Vol.21 (7), p.860-863
Hauptverfasser:	Wang, Yan, Yao, Qing Qiang, Wang, Mu Zou
Format:	Artikel
Sprache:	eng
Schlagworte:	(+)Clausenamide (−)Clausenamide AGP Chiral-AGP Enantiomers HPLC 固定相手性对映体液相色谱分离类似物糖蛋白绝对构型黄皮酰胺
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Zusammenfassung:	A method of high performance liquid chromatographic separation of clausenamide enantiomers with chiral-AGP（α_1-acid glycoprotein） stationary phases has been established.The absolute configurations of（-）clausenamide and（＋）clausenamide are 3S, 4R,5R,6S and 3R,4S,5S,6R,respectively.The present method has been used to analyze the（-）clausenamide and（＋）clausenamide and its analogues such as the major metabolite and synthetic derivatives of clausenamide.
ISSN:	1001-8417 1878-5964
DOI:	10.1016/j.cclet.2010.01.024