New polyhydroxylated metabolite derived from biotransformation of diosgenin by the white-rot fungus Coriolus versicolor
Microbial transformation of diosgenin(1) was carried out with the white-rot fungus,Coriolus versicolor.A new polyhydroxyl metabolite,(25R)-spirost-5-ene-3β,7β,21-triol(2),was obtained as a result of hydroxylation.Its structure was elucidated on the basis of 1D and 2D NMR as well as HR-ESI-MS spectro...
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Veröffentlicht in: | Chinese chemical letters 2010-04, Vol.21 (4), p.446-448 |
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creator | Wu, Guang Wei Li, Xiao Jun Gao, Yi Jia, Yuan Gao, Jin Ming |
description | Microbial transformation of diosgenin(1) was carried out with the white-rot fungus,Coriolus versicolor.A new polyhydroxyl metabolite,(25R)-spirost-5-ene-3β,7β,21-triol(2),was obtained as a result of hydroxylation.Its structure was elucidated on the basis of 1D and 2D NMR as well as HR-ESI-MS spectroscopic analysis. |
doi_str_mv | 10.1016/j.cclet.2009.11.018 |
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subjects | (25 R)-Spirost-5-ene-3β,7β,21-triol Biocatalysis Coriolus versicolor Diosgenin Microbial biotransformation |
title | New polyhydroxylated metabolite derived from biotransformation of diosgenin by the white-rot fungus Coriolus versicolor |
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