A green method for the synthesis of bis-indolylmethanes and 3,3 -indolyloxindole derivatives using cellulose sulfuric acid under solvent-free conditions

A highly efficient green protocol for the preparation of bis-indolylmethanes,bis-2-methylindolylmethanes,bis-1-methylindolylmethanes and 3,3'-diindolyloxindole derivatives from the reaction of indoles with various aldehydes and ketones in the presence of cellulose sulfuric acid under solvent-fr...

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Veröffentlicht in:Chinese chemical letters 2010-02, Vol.21 (2), p.183-186
Hauptverfasser: Alinezhad, Heshmatollah, Haghighi, Asefeh Hagh, Salehian, Fatemeh
Format: Artikel
Sprache:eng
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Zusammenfassung:A highly efficient green protocol for the preparation of bis-indolylmethanes,bis-2-methylindolylmethanes,bis-1-methylindolylmethanes and 3,3'-diindolyloxindole derivatives from the reaction of indoles with various aldehydes and ketones in the presence of cellulose sulfuric acid under solvent-free conditions is reported.The significant features of this procedure are high yields of the products,mild reaction,solvent-free condition and non-toxicity of the catalyst.
ISSN:1001-8417
1878-5964
DOI:10.1016/j.cclet.2009.09.001