Molecular imprinting of protein by coordinate interaction

In this article, a novel strong interaction by forming complex between bovine serum albumin (BSA) and copper ion was utilized for the preparation of molecular imprinted hydrogel in aqueous solution. Results show that the inclusion of copper ion in preparation can bridge the template BSA and function...

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Veröffentlicht in:Chinese chemical letters 2009-06, Vol.20 (6), p.747-750
Hauptverfasser: Wang, Jun, Hua, Zhen Dong, Chen, Zhi Yong, Li, Yuan Zong, Zhao, Mei Ping
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Sprache:eng
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Zusammenfassung:In this article, a novel strong interaction by forming complex between bovine serum albumin (BSA) and copper ion was utilized for the preparation of molecular imprinted hydrogel in aqueous solution. Results show that the inclusion of copper ion in preparation can bridge the template BSA and functional monomers together and improve the imprinting effect compared to the polymer made without copper ion added. High selectivity factor and large adsorption capacity are also observed for the obtained BSA-imprinted hydrogel.
ISSN:1001-8417
1878-5964
DOI:10.1016/j.cclet.2008.12.035