Polymeric complex micelle loaded with axially substituted silicon(IV) phthalocyanine

A novel axially substituted silicon(IV) phthalocyanine, namely di-pyridyloxy axially substituted silicon(IV) phthalocyanine 2 was synthesized and characterized by UV/vis, IR, elemental analysis, MS as well as 1H NMR spectroscopy. Hydrophobic 2 was encapsulated by amphiphilic triblock copolymer poly[N ɛ-(benzyloxycarbonyl-lysine]–poly(ethylene glycol)-poly [N ɛ-(benzyl oxycarbonyl) (PLL(Z)- b-PEG- b-PLL(Z)) to form hydrophobic 2-loaded polymeric complex micelle (PIC) (2-loaded PIC). Atom force microscopy (AFM) image showed that 2-loaded PIC formed a spherical nanocarrier with approximately 35–50 nm in diameter. The fluorescence intensity and lifetime of 2-loaded PIC was significantly enhanced by the incorporation 2 into PIC nanocarrier.