Development of mild and efficient method for synthesis of substituted flavones using oxalic acid catalyst

Oxalic acid has been used as a catalyst for intramolecular cyclisation of 2-hydroxychalcones to form flavones in good yields. The efficiency of the catalyst was proved with a variety of substrates ranging from electron-deficient to electron-rich aryl aldehydes and 2-hydroxychalcone.

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Veröffentlicht in:Chinese chemical letters 2009-02, Vol.20 (2), p.171-174
Hauptverfasser: Zambare, Abhay S., Sangshetti, Jaiprakash N., Kokare, Nagnnath D., Shinde, Devanand B.
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Sprache:eng
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Zusammenfassung:Oxalic acid has been used as a catalyst for intramolecular cyclisation of 2-hydroxychalcones to form flavones in good yields. The efficiency of the catalyst was proved with a variety of substrates ranging from electron-deficient to electron-rich aryl aldehydes and 2-hydroxychalcone.
ISSN:1001-8417
1878-5964
DOI:10.1016/j.cclet.2008.10.042