6-O-(Hydroxypropyltrimethylammonia)-β-cyclodextrin with Low Degree of Substitution: Convenient Preparation and its Application as a Chiral Selector in Capillary Electrophoresis

O6; A cationic cyclodextrin derivative 6-O-(hydroxypropyltrimethylammonia)-β-cyclodextrin (GTA-β-CD) with low degree of substitution was prepared through a convenient method in solid phase. The product could be used as a valuable chiral selector in the capillary electrophoresis (CE) separation of so...

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Veröffentlicht in:中国化学快报(英文版) 2006-03, Vol.17 (3), p.407-410
Hauptverfasser: Ming Gang ZHAO, Ai You HAO, Jian LI, Xiu Li LIN
Format: Artikel
Sprache:eng
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Zusammenfassung:O6; A cationic cyclodextrin derivative 6-O-(hydroxypropyltrimethylammonia)-β-cyclodextrin (GTA-β-CD) with low degree of substitution was prepared through a convenient method in solid phase. The product could be used as a valuable chiral selector in the capillary electrophoresis (CE) separation of some acidic drug enantiomers such as naproxen, ofloxacin,ibuprofen and warfarin.
ISSN:1001-8417