Regioselective Addition of Silyl Enolates to α,β-Unsaturated Aldehyde and its Acetal Catalyzed by MgI2 Etherate

Regioselective Addition of Silyl Enolates to α,β-Unsaturated Aldehyde and its Acetal Catalyzed by MgI2 Etherate

O6; Regioselective addition reactions of silyl enolates to α,β -unsaturated aldehyde and its acetal catalyzed by MgI2 etherate give aldol adducts (1, 2-addition) preferentially over Michael adducts (1, 4-addition). This unique regioselectivity is distinctly different with other Lewis acidic promoter...

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Veröffentlicht in:中国化学快报(英文版) 2003-08, Vol.14 (8), p.800-803
Hauptverfasser: Xing Xian ZHANG, Wei Dong Z.LI
Format: Artikel
Sprache:eng
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Zusammenfassung:O6; Regioselective addition reactions of silyl enolates to α,β -unsaturated aldehyde and its acetal catalyzed by MgI2 etherate give aldol adducts (1, 2-addition) preferentially over Michael adducts (1, 4-addition). This unique regioselectivity is distinctly different with other Lewis acidic promoters and may be attributed to the high oxyphilicity of IMg+.
ISSN:1001-8417