Synthesis of Alkylene-linked Dimers of (-)-Huperzine A

Synthesis of Alkylene-linked Dimers of (-)-Huperzine A

O6; Six alkylene-linked dimers of (-)-huperzineA (6) were prepared. All these dimers are less potent than (-)-Hup A in inhibition of AChE.

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Veröffentlicht in:中国化学快报(英文版) 2002, Vol.13 (1), p.23-26
Hauptverfasser: Guang Yi JIN, Xu Chang HE, Hai Yan ZHANG, Dong Lu BAI
Format: Artikel
Sprache:eng
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Zusammenfassung:O6; Six alkylene-linked dimers of (-)-huperzineA (6) were prepared. All these dimers are less potent than (-)-Hup A in inhibition of AChE.
ISSN:1001-8417