Recurrent Patterns and Factors Involved in Node-negative Advanced Gastric Cancer
Objective： To investigate the recurrent patterns and factors involved in node-negative advanced gastric cancer after curative resection. Patients and Methods： Clinicopathological characteristics and prognostic outcomes of 310 patients who had lymph node-negative advanced gastric adenocarcinoma and r...
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| Veröffentlicht in: | Chinese journal of cancer research 2010-12, Vol.22 (4), p.285-290 |
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| container_title | Chinese journal of cancer research |
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| creator | Liu, En-Yi Zhong, Mei-Zuo Liu, Cai-Gang Huang, Jin Liu, Wei Zeng, Shan Li, Bin Lu, Jing-Chen Li, Jian-Huang Jiang, Hai-Rong |
| description | Objective： To investigate the recurrent patterns and factors involved in node-negative advanced gastric cancer after curative resection. Patients and Methods： Clinicopathological characteristics and prognostic outcomes of 310 patients who had lymph node-negative advanced gastric adenocarcinoma and received curative resection between 2002 and 2006 were retrospectively evaluated. Results： Among the 300 patients, 15 （5.0%） had locoregional recurrence, 5 （1.7%） had lymph node recurrence, 27 （9.0%） had peritoneal seeding recurrence, and 21 （7.0%） had hematogenous metastasis. Using multivariate analysis, we found that the maximum tumor diameter （P=0.014）, histological type （P=0.001） and Borrmann type （P=0.033） were independent factors predicting the locoregional recurrence. Lymph node recurrence was significantly affected by lymph node dissection （P=0.029） and lymphovascular invasion （P=0.004）. Clinicopathological factors predicting the peritoneal seeding recurrence were the depth of invasion （P=0.001） and Borrmann type （P=0.002）. In addition, lymphovascular invasion （P=0.013） and histological type （P=0.001） were significantly associated with hematogenous metastasis. Conclusion： Node-negative advanced gastric cancer has a high amount of peritoneal seeding and hematogenous metastasis. |
| doi_str_mv | 10.1007/s11670-010-0285-3 |
| format | Article |
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Patients and Methods： Clinicopathological characteristics and prognostic outcomes of 310 patients who had lymph node-negative advanced gastric adenocarcinoma and received curative resection between 2002 and 2006 were retrospectively evaluated. Results： Among the 300 patients, 15 （5.0%） had locoregional recurrence, 5 （1.7%） had lymph node recurrence, 27 （9.0%） had peritoneal seeding recurrence, and 21 （7.0%） had hematogenous metastasis. Using multivariate analysis, we found that the maximum tumor diameter （P=0.014）, histological type （P=0.001） and Borrmann type （P=0.033） were independent factors predicting the locoregional recurrence. Lymph node recurrence was significantly affected by lymph node dissection （P=0.029） and lymphovascular invasion （P=0.004）. Clinicopathological factors predicting the peritoneal seeding recurrence were the depth of invasion （P=0.001） and Borrmann type （P=0.002）. In addition, lymphovascular invasion （P=0.013） and histological type （P=0.001） were significantly associated with hematogenous metastasis. Conclusion： Node-negative advanced gastric cancer has a high amount of peritoneal seeding and hematogenous metastasis.</description><identifier>ISSN: 1000-9604</identifier><identifier>EISSN: 1993-0631</identifier><identifier>DOI: 10.1007/s11670-010-0285-3</identifier><language>eng</language><publisher>Heidelberg: Chinese Anti-Cancer Association</publisher><subject>Medicine ; Medicine & Public Health ; Original Article</subject><ispartof>Chinese journal of cancer research, 2010-12, Vol.22 (4), p.285-290</ispartof><rights>Chinese Anti-Cancer Association and Springer Berlin Heidelberg 2010</rights><rights>Copyright © Wanfang Data Co. Ltd. All Rights Reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c299t-d2c39130a64b0266b319aecd20422542e3d9599f432c1c5f88f877080f8f58003</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Uhttp://image.cqvip.com/vip1000/qk/85190X/85190X.jpg</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids></links><search><creatorcontrib>Liu, En-Yi</creatorcontrib><creatorcontrib>Zhong, Mei-Zuo</creatorcontrib><creatorcontrib>Liu, Cai-Gang</creatorcontrib><creatorcontrib>Huang, Jin</creatorcontrib><creatorcontrib>Liu, Wei</creatorcontrib><creatorcontrib>Zeng, Shan</creatorcontrib><creatorcontrib>Li, Bin</creatorcontrib><creatorcontrib>Lu, Jing-Chen</creatorcontrib><creatorcontrib>Li, Jian-Huang</creatorcontrib><creatorcontrib>Jiang, Hai-Rong</creatorcontrib><title>Recurrent Patterns and Factors Involved in Node-negative Advanced Gastric Cancer</title><title>Chinese journal of cancer research</title><addtitle>Chin. J. Cancer Res</addtitle><addtitle>Chinese Journal of Cancer Research</addtitle><description>Objective： To investigate the recurrent patterns and factors involved in node-negative advanced gastric cancer after curative resection. Patients and Methods： Clinicopathological characteristics and prognostic outcomes of 310 patients who had lymph node-negative advanced gastric adenocarcinoma and received curative resection between 2002 and 2006 were retrospectively evaluated. Results： Among the 300 patients, 15 （5.0%） had locoregional recurrence, 5 （1.7%） had lymph node recurrence, 27 （9.0%） had peritoneal seeding recurrence, and 21 （7.0%） had hematogenous metastasis. Using multivariate analysis, we found that the maximum tumor diameter （P=0.014）, histological type （P=0.001） and Borrmann type （P=0.033） were independent factors predicting the locoregional recurrence. Lymph node recurrence was significantly affected by lymph node dissection （P=0.029） and lymphovascular invasion （P=0.004）. Clinicopathological factors predicting the peritoneal seeding recurrence were the depth of invasion （P=0.001） and Borrmann type （P=0.002）. In addition, lymphovascular invasion （P=0.013） and histological type （P=0.001） were significantly associated with hematogenous metastasis. Conclusion： Node-negative advanced gastric cancer has a high amount of peritoneal seeding and hematogenous metastasis.</description><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Original Article</subject><issn>1000-9604</issn><issn>1993-0631</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><recordid>eNp9kE1LAzEQhoMoWKs_wFvw4ik6SfYrx1JsLRQtoueQzSbr1prVZLvS_npTtuDNQ5gM8z4z8CB0TeGOAuT3gdIsBwI0PlakhJ-gERWCE8g4PY1_ACAig-QcXYSwBkjzFOgIrV6M3npvXIdXquuMdwErV-GZ0l3rA164vt30psKNw09tZYgzteqa3uBJ1Sun42SuQucbjaeH1l-iM6s2wVwd6xi9zR5ep49k-TxfTCdLopkQHamY5oJyUFlSAsuyklOhjK4YJIylCTO8EqkQNuFMU53aorBFnkMBtrBpAcDH6HbY-6OcVa6W63brXbwo97Xa79YsqoAkqolJOiS1b0Pwxsov33wqv5MU5EGeHOTJSMiDPMkjwwYmxKyrjf9b_x90czz03rr6O3KyVPrDNhsjecYYZyLhv5wse5Q</recordid><startdate>20101201</startdate><enddate>20101201</enddate><creator>Liu, En-Yi</creator><creator>Zhong, Mei-Zuo</creator><creator>Liu, Cai-Gang</creator><creator>Huang, Jin</creator><creator>Liu, Wei</creator><creator>Zeng, Shan</creator><creator>Li, Bin</creator><creator>Lu, Jing-Chen</creator><creator>Li, Jian-Huang</creator><creator>Jiang, Hai-Rong</creator><general>Chinese Anti-Cancer Association</general><general>Department of Oncology,Xiangya Hospital,Central South University,Changsha 410008,China%Department of Surgical Oncology,First Hospital,China Medial University,Shenyang 110001,China</general><scope>2RA</scope><scope>92L</scope><scope>CQIGP</scope><scope>W91</scope><scope>~WA</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>2B.</scope><scope>4A8</scope><scope>92I</scope><scope>93N</scope><scope>PSX</scope><scope>TCJ</scope></search><sort><creationdate>20101201</creationdate><title>Recurrent Patterns and Factors Involved in Node-negative Advanced Gastric Cancer</title><author>Liu, En-Yi ; Zhong, Mei-Zuo ; Liu, Cai-Gang ; Huang, Jin ; Liu, Wei ; Zeng, Shan ; Li, Bin ; Lu, Jing-Chen ; Li, Jian-Huang ; Jiang, Hai-Rong</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c299t-d2c39130a64b0266b319aecd20422542e3d9599f432c1c5f88f877080f8f58003</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Original Article</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Liu, En-Yi</creatorcontrib><creatorcontrib>Zhong, Mei-Zuo</creatorcontrib><creatorcontrib>Liu, Cai-Gang</creatorcontrib><creatorcontrib>Huang, Jin</creatorcontrib><creatorcontrib>Liu, Wei</creatorcontrib><creatorcontrib>Zeng, Shan</creatorcontrib><creatorcontrib>Li, Bin</creatorcontrib><creatorcontrib>Lu, Jing-Chen</creatorcontrib><creatorcontrib>Li, Jian-Huang</creatorcontrib><creatorcontrib>Jiang, Hai-Rong</creatorcontrib><collection>维普_期刊</collection><collection>中文科技期刊数据库-CALIS站点</collection><collection>维普中文期刊数据库</collection><collection>中文科技期刊数据库-医药卫生</collection><collection>中文科技期刊数据库- 镜像站点</collection><collection>CrossRef</collection><collection>Wanfang Data Journals - Hong Kong</collection><collection>WANFANG Data Centre</collection><collection>Wanfang Data Journals</collection><collection>万方数据期刊 - 香港版</collection><collection>China Online Journals (COJ)</collection><collection>China Online Journals (COJ)</collection><jtitle>Chinese journal of cancer research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Liu, En-Yi</au><au>Zhong, Mei-Zuo</au><au>Liu, Cai-Gang</au><au>Huang, Jin</au><au>Liu, Wei</au><au>Zeng, Shan</au><au>Li, Bin</au><au>Lu, Jing-Chen</au><au>Li, Jian-Huang</au><au>Jiang, Hai-Rong</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Recurrent Patterns and Factors Involved in Node-negative Advanced Gastric Cancer</atitle><jtitle>Chinese journal of cancer research</jtitle><stitle>Chin. J. Cancer Res</stitle><addtitle>Chinese Journal of Cancer Research</addtitle><date>2010-12-01</date><risdate>2010</risdate><volume>22</volume><issue>4</issue><spage>285</spage><epage>290</epage><pages>285-290</pages><issn>1000-9604</issn><eissn>1993-0631</eissn><abstract>Objective： To investigate the recurrent patterns and factors involved in node-negative advanced gastric cancer after curative resection. Patients and Methods： Clinicopathological characteristics and prognostic outcomes of 310 patients who had lymph node-negative advanced gastric adenocarcinoma and received curative resection between 2002 and 2006 were retrospectively evaluated. Results： Among the 300 patients, 15 （5.0%） had locoregional recurrence, 5 （1.7%） had lymph node recurrence, 27 （9.0%） had peritoneal seeding recurrence, and 21 （7.0%） had hematogenous metastasis. Using multivariate analysis, we found that the maximum tumor diameter （P=0.014）, histological type （P=0.001） and Borrmann type （P=0.033） were independent factors predicting the locoregional recurrence. Lymph node recurrence was significantly affected by lymph node dissection （P=0.029） and lymphovascular invasion （P=0.004）. Clinicopathological factors predicting the peritoneal seeding recurrence were the depth of invasion （P=0.001） and Borrmann type （P=0.002）. In addition, lymphovascular invasion （P=0.013） and histological type （P=0.001） were significantly associated with hematogenous metastasis. Conclusion： Node-negative advanced gastric cancer has a high amount of peritoneal seeding and hematogenous metastasis.</abstract><cop>Heidelberg</cop><pub>Chinese Anti-Cancer Association</pub><doi>10.1007/s11670-010-0285-3</doi><tpages>6</tpages></addata></record> |
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| title | Recurrent Patterns and Factors Involved in Node-negative Advanced Gastric Cancer |
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