The Comparison Study of Renin and Angiotensin A H Levels on Normal Tension Glaucoma Patients and Normal Individuals

R77; Purpose: To investigate the levels of renin-angiotension system (RAS) components in normal tension glaucoma patients and normal controls.Methods: Blood samples were obtained from 11 normal tension glaucoma(NTG)patients and 11 age and sex matched controls. The levels of renin and angiotensin A Ⅱ of 11 NTG patients and normal controls were examined by radio-immunity test. Statistical analyses were performed by paired t test.Results :The levels of renin of NTG patients and normal controls are (769.085±183.217) pg/ml/n and (822.035±124.140) pg/ml/n, while the levels of angiotensin A Ⅱ of NTG patients and normal controls are (37.347±10.669)pg/ml and (24.836±10.665)pg/ml respectively. No statistically significant differences were observed between the levels of renin and angiotensin among NTG patients and normal controls.Conclusion:There were not many abnormalities of the levels of circulating rennin and angiotensin A Ⅱ of NTG patients in our study.