Ultrasonic-assisted synthesis and strepavidin conjugation of amino-magnetic nanoparticles

MNPs are widely used in biotechnology, magnetic resonance imaging, catalysis and other areas. In this paper, we propose a simple, quick, inexpensive and efficient way to prepare amino-MNPs with sonication-assisted process. The amino-MNPs prepared by hydrolyzing TEOS and APS were characterized by SEM...

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Veröffentlicht in:Nuclear science and techniques 2008-12, Vol.19 (6), p.370-375
Hauptverfasser: LIU, Li, JIAO, Qinghua, PENG, Cheng, HE, Shijiang, WANG, Lihua
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Sprache:eng
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Zusammenfassung:MNPs are widely used in biotechnology, magnetic resonance imaging, catalysis and other areas. In this paper, we propose a simple, quick, inexpensive and efficient way to prepare amino-MNPs with sonication-assisted process. The amino-MNPs prepared by hydrolyzing TEOS and APS were characterized by SEM, TEM and FTIR. Conjugation of SA and amino-MNPs was also studied. The biotin bound capacity of prepared S A coated amino-MNPs was 1.824 nmol/mg, which well meet the need of biological application.
ISSN:1001-8042
2210-3147
DOI:10.1016/S1001-8042(09)60021-X