Isolation and Identification of Two New Polyhydroxylated Sterols from Soft Coral Sinularia sp

Isolation and Identification of Two New Polyhydroxylated Sterols from Soft Coral Sinularia sp

Two new polyhydroxysteroids, 12β,16β,20-trihydroxycholesta-1,4-dien-3-one 16-acetate（1） and 24- methyl-12β,16β,20-trihydroxycholesta-1,4-dien-3-one（2） were isolated from octocoral Sinularia sp. Their structures were elucidated primarily on the basis of 1D and 2D NMR and the mass spectroscopic studie...

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Veröffentlicht in:Chemical research in Chinese universities 2011-03, Vol.27 (2), p.217-220
1. Verfasser: LIAO Xiao-jian TANG Li-dan LIANG Yuan-wei GENG Hua-wei XU Shi-hai
Format: Artikel
Sprache:eng
Schlagworte:
Sinularia
二维核磁共振
多羟基甾醇
肿瘤细胞株
软珊瑚
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Zusammenfassung:Two new polyhydroxysteroids, 12β,16β,20-trihydroxycholesta-1,4-dien-3-one 16-acetate（1） and 24- methyl-12β,16β,20-trihydroxycholesta-1,4-dien-3-one（2） were isolated from octocoral Sinularia sp. Their structures were elucidated primarily on the basis of 1D and 2D NMR and the mass spectroscopic studies. The cytotoxicity of these compounds against three tumor cell lines was also reported.
ISSN:1005-9040
2210-3171