Cytotoxic Diarylheptanoids from Pericarps of Juglans Cathayensis Dode

Cytotoxic Diarylheptanoids from Pericarps of Juglans Cathayensis Dode

A novel diarylheptanoid, named Jugcathanin（1）, along with two known diarylheptanoids（2,3）, were isolated from the fresh pericarps ofduglans Cathayensis Dode. A known triterpene（4） and a known aphthaoquinone（5） were also isolated from the plant. Their structures were elucidated on the basis of spectr...

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Veröffentlicht in:Chemical research in Chinese universities 2008-07, Vol.24 (4), p.427-429
Hauptverfasser: LI, Yi-xiu, RUAN, Han-li, ZHOU, Xue-feng, ZHANG, Yong-hui, PI, Hui-fang, WU, Ji-zhou
Format: Artikel
Sprache:eng
Schlagworte:
Antitumor activity
Jugcathanin
Juglans Cathayensis Dode
抗癌活性
有效成分
细胞毒素
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Zusammenfassung:A novel diarylheptanoid, named Jugcathanin（1）, along with two known diarylheptanoids（2,3）, were isolated from the fresh pericarps ofduglans Cathayensis Dode. A known triterpene（4） and a known aphthaoquinone（5） were also isolated from the plant. Their structures were elucidated on the basis of spectroscopic studies. All the compounds exhibited moderate cytotoxicities against human Hela, HepG2, and HL-60 cell lines.
ISSN:1005-9040
2210-3171
DOI:10.1016/S1005-9040(08)60089-6