Plasmids of Distinct IncK Lineages Show Compatible Phenotypes

IncK plasmids are some of the main carriers of and genes and show high similarity to other plasmids belonging to the I complex, including IncB/O plasmids. Here, we studied the phylogenetic relationship of 37 newly sequenced IncK and IncB/O plasmids. We show that IncK plasmids can be divided into two...

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Veröffentlicht in:	Antimicrobial agents and chemotherapy 2017-03, Vol.61 (3)
Hauptverfasser:	Rozwandowicz, Marta, Brouwer, Michael S M, Zomer, Aldert L, Bossers, Alex, Harders, Frank, Mevius, Dik J, Wagenaar, Jaap A, Hordijk, Joost
Format:	Artikel
Sprache:	eng
Schlagworte:	beta-Lactamases beta-Lactamases - genetics beta-Lactamases - metabolism Conjugation, Genetic Epidemiology and Surveillance Escherichia coli Escherichia coli - classification Escherichia coli - enzymology Escherichia coli - genetics Escherichia coli - isolation & purification Escherichia coli Infections - microbiology Escherichia coli Proteins Escherichia coli Proteins - genetics Escherichia coli Proteins - metabolism Gene Expression Humans IncK Incompatibility Phenotype Phylogeny Plasmid Plasmids Plasmids - chemistry Plasmids - classification Plasmids - metabolism Sequence Analysis, DNA Transformation, Bacterial
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Beschreibung
Zusammenfassung:	IncK plasmids are some of the main carriers of and genes and show high similarity to other plasmids belonging to the I complex, including IncB/O plasmids. Here, we studied the phylogenetic relationship of 37 newly sequenced IncK and IncB/O plasmids. We show that IncK plasmids can be divided into two compatible lineages named IncK1 and IncK2.
ISSN:	0066-4804 1098-6596
DOI:	10.1128/aac.01954-16