Commentary: “A systems view on the future of medicine: Inspiration from Chinese medicine?”

Chinese medicine could serve as a source of inspiration for drug development. Using systems biology in combination with reverse pharmacology is a novel way for the discovery of novel biological active compounds and targets as well as for proving the occurrence of synergy and prodrugs. A key factor f...

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Veröffentlicht in:	Journal of ethnopharmacology 2009-01, Vol.121 (3), p.479-481
Hauptverfasser:	Verpoorte, R., Crommelin, D., Danhof, M., Gilissen, L.J.W.J., Schuitmaker, H., van der Greef, J., Witkamp, R.F.
Format:	Artikel
Sprache:	eng
Schlagworte:	biology Chinese medicine Drug Design Drug development Drug Synergism Drug Therapy, Combination Drugs, Chinese Herbal - therapeutic use Evidence-based traditional medicine Humans Medicine, Chinese Traditional Metabolomics Polypharmacy Synergism Systems Biology
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	Chinese medicine could serve as a source of inspiration for drug development. Using systems biology in combination with reverse pharmacology is a novel way for the discovery of novel biological active compounds and targets as well as for proving the occurrence of synergy and prodrugs. A key factor for coming to evidence-based Chinese medicine will be the quality control. Metabolomics is a very promising tool for this purpose.
ISSN:	0378-8741 1872-7573
DOI:	10.1016/j.jep.2008.11.005