Lifestyle factors for the prevention of inflammatory bowel disease

Lifestyle factors for the prevention of inflammatory bowel disease

ObjectiveTo estimate the proportion of cases of Crohn's disease (CD) and ulcerative colitis (UC) that could be prevented by modifiable lifestyle factors. DesignIn a prospective cohort study of US adults from the Nurses' Health Study (NHS; n=72 290), NHSII (n=93 909) and Health Professional...

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Hauptverfasser: Lopes, Emily W, Chan, Simon S. M, Song, Mingyang, Ludvigsson, Jonas F, Hakansson, Niclas, Lochhead, Paul, Clark, Allan, Burke, Kristin E, Ananthakrishnan, Ashwin N, Cross, Amanda J, Palli, Domenico, Bergmann, Manuela M, Richter, James M, Chan, Andrew T, Olen, Ola, Wolk, Alicja, Khalili, Hamed
Format: Artikel
Sprache:eng
Schlagworte:
crohn's disease
diet
epidemiology
Gastroenterologi
Gastroenterology and Hepatology
ulcerative colitis
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Zusammenfassung:ObjectiveTo estimate the proportion of cases of Crohn's disease (CD) and ulcerative colitis (UC) that could be prevented by modifiable lifestyle factors. DesignIn a prospective cohort study of US adults from the Nurses' Health Study (NHS; n=72 290), NHSII (n=93 909) and Health Professionals Follow-up Study (HPFS; n=41 871), we created modifiable risk scores (MRS; 0-6) for CD and UC based on established lifestyle risk factors, and healthy lifestyle scores (HLS; 0-9) derived from American healthy lifestyle recommendations. We calculated the population attributable risk by comparing the incidence of CD and UC between low-risk (CD-MRS
DOI:10.1136/gutjnl-2022-328174