Association between β-blocker dose and cardiovascular outcomes after myocardial infarction : insights from the SWEDEHEART registry

Association between β-blocker dose and cardiovascular outcomes after myocardial infarction : insights from the SWEDEHEART registry

Aims Dose-dependent effects of β-blockers on survival and cardiovascular outcomes after myocardial infarction (MI) are not well understood. We investigated the long-term risk of cardiovascular events in patients with different doses of β-blockers after MI. Methods and results This was a nationwide o...

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Hauptverfasser: Mars, Katarina, Wallert, John, Held, Claes, Humphries, Sophia, Pingel, Ronnie, Jernberg, Tomas, Olsson, Erik M. G, Hofmann, Robin
Format: Artikel
Sprache:eng
Schlagworte:
Adrenergic beta-antagonist
Cardiac and Cardiovascular Systems
Kardiologi
Mortality
Myocardial infarction
Nationwide register data
Prognosis
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Zusammenfassung:Aims Dose-dependent effects of β-blockers on survival and cardiovascular outcomes after myocardial infarction (MI) are not well understood. We investigated the long-term risk of cardiovascular events in patients with different doses of β-blockers after MI. Methods and results This was a nationwide observational study linking morbidity, mortality, socioeconomic, and medication data from Swedish national registries. Between 2006 and 2015, 97 575 unique patients with first-time MI were included. In total, 33 126 (33.9%) patients were discharged with ≥50% of the target β-blocker dose and 64 449 (66.1%) patients with
DOI:10.1093/ehjacc/zuaa002