Bioactive glass S53P4 eradicatesStaphylococcus aureusin biofilm/planktonic statesin vitro

Bioactive glass S53P4 eradicatesStaphylococcus aureusin biofilm/planktonic statesin vitro

Background:Increasing antimicrobial resistance to antibiotics is a substantial health threat. Bioactive glass S53P4 (BAG) has an antimicrobial effect that can reduce the use of antibiotics. The aim of this study was to evaluate the antimicrobial efficacy of BAGin vitroon staphylococci in biofilm and...

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Hauptverfasser: Gronseth, Torstein, Vestby, Lene K, Nesse, Live L, von Unge, Magnus, Silvola, Juha T
Format: Artikel
Sprache:eng
Schlagworte:
BAG
biofilm
confocal laser scanning microscopy
Microbiology
Mikrobiologi
Staphylococcus aureus
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Zusammenfassung:Background:Increasing antimicrobial resistance to antibiotics is a substantial health threat. Bioactive glass S53P4 (BAG) has an antimicrobial effect that can reduce the use of antibiotics. The aim of this study was to evaluate the antimicrobial efficacy of BAGin vitroon staphylococci in biofilm and in planktonic form. Secondary aims were to investigate whether supernatant fluid primed from BAG retains the antibacterial capacity and if ciprofloxacin enhances the effect. Methods:BAG-S53P4 granules,
DOI:10.1080/03009734.2020.1765908